CLI/TUI for computational biology and drug discovery on the .bloom* platform
npm install @ivybiosciences/ivybloom-cli
Terminal-native computational biology and drug discovery
Documentation ยท
API Reference
---
``bash`
npm install -g @ivybiosciences/ivybloom-cli
Or run directly with npx:
`bash`
npx @ivybiosciences/ivybloom-cli tui
`bash`
ivybloom auth login # Authenticate
ivybloom tui # Launch TUI

The TUI is your command center for computational biology workflows.
Converse with an AI assistant specialized in computational biology:
- Ask questions about protein structure, drug design, and molecular analysis
- Get guidance on which tools to use for your research
- Receive explanations of results and next steps
Run scientific computations directly from the chat:
| Tool | Description |
|------|-------------|
| ESMFold | Protein structure prediction |
| AlphaFold | Deep learning structure prediction |
| REINVENT | Drug molecule generation |
| ADMET | Toxicity & solubility analysis |
| Docking | Protein-ligand binding simulations |
Tools execute with a Cursor-style approval flow โ review commands before they run.
Track long-running computations in real-time:
``
โโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโ
โ ESMFold Structure Prediction โ
โ โโโโโโโโโโโโโโโโโโโโโโโโโโโโโโ 67% โ
โ Phase: Computing attention maps โ
โโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโโ
- View progress percentage and current phase
- Stream logs as jobs execute
- Get notified when jobs complete
| Key | Action |
|-----|--------|
| @ | Attach files (sequences, structures, molecules) |!
| | Browse and run available tools |/
| | Command palette |y
| / n | Approve / deny tool execution |Tab
| | Toggle context panel |?
| | Show help |
For scripting and automation:
`bashTools
ivybloom tools list
ivybloom tools run esmfold --sequence "MKFLILLFN..."
| Platform | Architecture |
|----------|--------------|
| macOS | Intel & Apple Silicon |
| Linux | x64 & arm64 |
| Windows | x64 |
---
Built by Ivy Biosciences